Can late pregnancy increase your child’s risk of cancer? Here’s the truth!


As more women delay motherhood for various personal and professional reasons, concerns about the potential health risks associated with late pregnancy have come to the fore. One of the questions is whether having children later in life increases the risk of developing cancer. Let’s understand!



Published: Sep 24, 2024 4:43 pm IST


By Onam Gupta

Can Late Pregnancy Increase Your Child’s Risk of Cancer? Here’s the Truth!

In recent years, many people have chosen to have children later in life. As this trend continues, an important question arises: does being an older parent increase the risk of cancer for their child? This question has sparked debate among experts, with some studies suggesting a possible link between parental age and cancer risk in offspring.

What is childhood cancer?

Childhood cancer refers to cancer that occurs in children from birth through adolescence. Although cancer is less common in children than in adults, it remains a major concern and the leading cause of death from disease among children in many countries. Childhood cancers are distinct from those that occur in adults, both in terms of their varieties and their behavior.

Parental age and cancer risk

Research indicates that older parental age (i.e., 40 years or older) at the time of conception may be associated with an increased risk of certain types of cancer in children. This connection is thought to arise from the accumulation of genetic mutations in sperm and eggs as people age. Studies have particularly highlighted an increased risk of childhood leukemia, brain tumors, and retinoblastoma among children born to older fathers. Although the overall risk of cancer in children remains low, it is critical to understand this potential increase.

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Signs of childhood cancer

According to Dr. Sunit Lokwani, Medical Oncologist and Clinical Hematologist, HCG Cancer Centre, Indore, “It is crucial to be aware of the signs of childhood cancer as early detection can significantly impact treatment outcomes. Symptoms may vary depending on the type and location of the cancer, but some general signs to look out for are:”

  • Unexplained weight loss: Significant or rapid weight loss without a known reason.
  • Persistent pain: Ongoing pain that does not improve with standard treatments, such as headaches or back pain.
  • Lumps or swelling: Noticeable lumps or swelling in the abdomen, neck, or other areas.
  • Frequent infections: Frequent or serious infections that seem unusual or are difficult to treat.
  • Unusual bruising or bleeding: Unexplained bruising, bleeding, or petechiae (small red or purple spots on the skin).
  • Prolonged fever: persistent fever that does not respond to typical treatments.
  • Fatigue or weakness: Unusual, prolonged tiredness or weakness, particularly if it affects daily activities.
  • Vision changes or eye problems: Persistent changes in vision or problems with the alignment and appearance of the eyes, such as a white pupil (leukocoria).

What can parents do?

For older parents who are concerned about their children’s cancer risk, there are several proactive steps that can be taken to mitigate potential risks. Maintaining a healthy lifestyle before and during pregnancy is critical, including eating a balanced diet, getting regular exercise, and avoiding harmful substances such as tobacco and alcohol. Regular prenatal care and genetic counseling are also valuable, as they can help identify risk factors early and facilitate timely interventions.

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While being an older parent may be associated with a slightly higher risk of certain types of cancer in children, it is essential to note that this risk is still relatively low. By taking a proactive approach that includes maintaining a healthy lifestyle, seeking regular medical care, and being on the lookout for early warning signs of cancer, older parents can effectively manage potential risks and support their children’s health. Adopting these practices ensures that age does not become a barrier to providing a healthy and fulfilling life for their child.






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