How everyday traffic jam can lead to fatty liver risk?


Did you know that regular traffic jams can also affect liver health? This is what the new study says.



Posted: January 31, 2025 9:05 PM IST


By Ians

Only 10 micrograms daily of PM2.5 particles derived from traffic can be enough to damage their liver and increase the risk of fatty liver disease associated with metabolic, according to a new study on Friday.

The fatty liver, also called hepatic steatosis, is the most common liver disease worldwide. The disease occurs due to excess fat accumulation in liver cells.

Previous studies have indicated lifestyle factors as a bad diet, lack of exercise and excessive alcohol as the main reason behind the fatty liver.

The new research carried out in mice suggests that our environment, particularly exposure to traffic air pollution, can also contribute to the disease.

“We think that air pollution is harmful to people’s lungs, but it has a broader impact on health, even in the liver,” said Principal and Professor Hui Chen of the Sydney Technological University (UTS).

“When we inhale air pollution, very small particles known as PM2.5 enter the bloodstream through the lungs. The liver, which filters toxins of the blood, accumulates these substances, including heavy metals such as arsenic, lead, nickel and zinc, “Chen added.

The study, published in the Journal of Environmental Sciences, said the team presented mice to 10 micrograms of PM2.5 particles derived from traffic daily.

  प्रेग्नेंसी में नॉनवेज खाना सही है या नहीं? जानिए क्या कहती है रिसर्च

The team measured inflammation, fibrosis and changes in sugars and liver fats at four, eight and 12 weeks.

Although there was no significant change in four weeks for eight weeks, there was an interruption in the normal metabolic function of the liver. And at 12 weeks, significant changes were visible: 64 specific functional proteins in the liver showed changes. Many of these were linked to conditions such as fatty liver disease and immune system dysfunction.

Exposure to air pollution particles caused the most immune cells to accumulate in the liver, increasing inflammation. He also led to more scar tissue formation, the team said.

They also found potentially harmful fats such as triglycerides, diacilglyceroles and ceramids increased in the liver of mice.






Source link

Leave a Comment