According to a recent study, people with high fat stored in the muscles can risk their health.
People with hidden fat bags within their muscles have a greater risk of dying or being hospitalized by a heart attack or heart failure, regardless of their body mass index, according to the investigation on Monday. The new study, published in European Heart Journal, adds evidence that existing measures, such as the body mass index (BMI) or the circumference of the waist, are not suitable for assessing the risk of heart disease with precision for all people .
The study showed that people with the highest amounts of fat stored in their muscles were more likely to have damage to small blood vessels that serve to the heart (coronary microvascular dysfunction or CMD). They were also more likely to die or be hospitalized in heart disease.
People who had high levels of intermuscular fat and evidence of CMD had an especially high risk of death, heart attack and heart failure. “Knowing that intermuscular fat increases the risk of heart disease gives us another way to identify people who have a high risk, regardless of their body mass index. These findings could be particularly important to understand the effects of the heart of the therapies based on the modifying and muscle modifier, including the new kind of agonist agonists of the peptide-1 peptide-like glucagon, “said Professor Viviany Taqueti, director, director of the heart stress laboratory in Brigham and Women Hospital, USA.
The study analyzed the muscle and the different types of fat in 669 people to understand how body composition can influence small blood vessels or the “microcirculation” of the heart, as well as the future risk of heart failure, heart attack and death.
These were followed for about six years. In addition to verifying how well their hearts worked, the team also used computerized tomographs to analyze the body composition of each patient, measuring the amounts and location of fat and muscle in a section of their torso.
In addition, the team calculated the relationship between intermuscular fat and total muscle plus fat, a measurement called the fatty muscle fraction. For each 1 percent increase in the fraction of fatty muscle, there was a 2 percent increase in the risk of CMD and a 7 percent higher risk risk, regardless of other known risk factors and mass index bodily.
On the other hand, people with the highest amounts of lean muscle had a lower risk. The fat stored under the skin (subcutaneous fat) did not increase the risk.
“Compared to subcutaneous fat, fat stored in the muscles may be contributing to inflammation and altered glucose metabolism, which leads to insulin resistance and metabolic syndrome.
In turn, these chronic insults can cause damage to blood vessels, including those that supply heart and heart muscle themselves, ”said Professor Taqueti.
The equipment is evaluating the impact of treatment strategies that include exercise, nutrition, weight loss or surgery medications, body composition and metabolic heart disease, to help reduce the risk of people with fatty muscles.
