Researchers Led by Albert Einstein College of Medicine, Montefiore Health System, Regenstrief Institute and IU School of Medicine will evaluate the test in urban and rural communities
BRONX, New York, December 8, 2022 /PRNewswire/ — Researchers from Albert Einstein College of Medicine, Montefiore Health System, Regenstrief InstituteY Indiana University School of Medicine have received a $11 million grant from the National Institutes of Health (NIH) to evaluate a test developed by Einstein to assess cognitive decline and dementia. The 5-minute screening tool was designed for people of a variety of racial and ethnic backgrounds, educational levels, and socioeconomic circumstances with the goal of reducing disparities in the diagnosis and treatment of dementia and predementia and improving dementia care. usually.
“With Alzheimer’s becoming more common, we must find a way to involve more physicians in diagnosing the disease and its precursor conditions and directing people to the appropriate care and support services,” he said. joe vergheseMBBS, MSThe grant’s principal investigator and chief of the unified divisions of geriatrics in the department of medicine and cognitive and motor aging in the Saul R. Korey Department of Neurology at Einstein and Montefiore.
The Rising Tide of Alzheimer’s Disease
According to the Alzheimer’s Association, 6.5 million Americans age 65 and older are living with Alzheimer’s disease, and the number is expected to rise to 12.7 million by 2040. But not everyone is affected equally: 19 % of African Americans and 14% of Hispanics age People 65 and older are diagnosed with Alzheimer’s disease, compared to 10% of whites. Despite this, black participants in Alzheimer’s disease research studies they were 35% less likely to be diagnosed than white participants and were diagnosed with more severe symptoms.
Traditionally, neurologists diagnose Alzheimer’s disease or its precursor, mild cognitive impairment (MCI), after a lengthy evaluation. This poses a significant challenge for many groups: people with limited access to specialty care (including people from historically marginalized groups), as well as people living in poverty, in rural areas, or who require a referral from a primary care physician who can Not recognizing your symptoms.
“Primary care physicians are on the front lines of care for people with dementia, but it is challenging for them to make diagnoses; in fact, more than 50% of dementia cases are missed during primary care appointments. “, said Malaz Boustani, MD, MPH, co-principal investigator for the grant and founding director of the Center for Health Innovation and Implementation at the IU School of Medicine. “The 5-Cog detection paradigm seeks to address this challenge by providing a tool that requires no special equipment or training, is inexpensive, is available in English and Spanish, and takes just five minutes.” He is also a research scientist at the Regenstrief Institute.
A novel test
The 5-Cog assessment involves a picture-based memory impairment screening test, a brief picture-based symbol matching, and confirmation that a patient has cognitive complaints and mobility issues. Previous research has found that image-based assessment effectively negates the influences that result from a person’s preferred language, education level, and gender. Having previously validated the 5-Cog evaluation in a clinical site, the investigators will now evaluate the test in real-world primary care settings.
The study will enroll 6,600 participants presenting with cognitive problems at 22 primary care clinics in the bronx Y Indiana. The electronic medical record system will request primary care teams to perform the assessment. Responses will automatically be classified as “normal” or “abnormal” based on the results, and care teams will be provided with a decision tree to ensure patients receive appropriate support and follow-up care.
“Early diagnosis and treatment of dementia and MCI may allow people to stay in their homes longer and help families make appropriate plans,” said Dr. Verghese. “It also gives people the opportunity to make lifestyle changes to improve the trajectory of their disease.”
“5 Cog Battery to Improve Detection of Cognitive Impairment and Dementiais funded by the National Institute of Neurological Disorders and Stroke, part of the NIH. The kit also includes Emmeline AyersMPH, in Einstein; nicole hunterPhD, MHSA, paul dexterMD, both from Regenstrief and IU School of Medicine; rich holdenPh.D., MS, Regenstrief and indiana university School of Public Health-Bloomington; Y Sujuan GaoPh.D., IU School of Medicine.
On Albert Einstein College of Medicine
Albert Einstein College of Medicine is a research-intensive medical school. For more than 60 years, the diverse faculty and staff have set the standard for excellence in medical and graduate education and patient-centered clinical care and have made significant contributions to scientific research that improve human health in their communities. and beyond. Its mission is to prepare a diverse body of students to become compassionate physicians and innovative scientific researchers, and to create new knowledge. Einstein is affiliated with Montefiore Health System and Yeshiva University.
About Montefiore Health System
Montefiore Health System is one of New York world-class academic health systems and is a recognized leader in providing exceptional quality, personalized and accountable care to approximately three million people in communities around the world. bronx, Westchesterand the Hudson Valley. It is made up of 10 hospitals, including the Montefiore Children’s Hospital, Burke Rehabilitation Hospital and more than 200 outpatient ambulatory care sites. Advanced clinical and translational research at its medical school, Albert Einstein College of Medicine, directly informs patient care and improves outcomes. From the Montefiore-Einstein Centers of Excellence in cancer, cardiology and vascular care, pediatrics and transplantation, to its preeminent school health program, Montefiore is a fully integrated health care system that provides coordinated, comprehensive care for patients and their families. For more information please visit www.montefiore.org. follow us Twitter Y instagram Y LinkedInor visit us at Facebook Y Youtube.
About the Regenstrief Institute
Founded in 1969 in indianapolisthe Regenstrief Institute is a local, national and global leader dedicated to a world where better information empowers people to end disease and achieve true health. A key research partner for indiana university, Regenstrief and its scientific researchers are responsible for an increasing number of important innovations and health studies. Examples range from the development of global health information technology standards that enable the use and interoperability of electronic health records to improve doctor-patient communications, to the creation of models of care that inform practice and improve lives of patients around the world.
sam regenstriefa successful national businessman Connersville, Indiana, founded the institute with the goal of making healthcare more efficient and accessible to all. His vision continues to guide the institute’s research mission.
About the IU School of Medicine
IU School of Medicine It is the largest medical school in the US and is ranked annually among the best medical schools in the country by US News & World Report. The school offers high-quality medical education, access to leading medical research, and a rich campus life in nine Indiana cities, including rural and urban areas consistently recognized for their livability.
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