Bariatric surgery more effective than lifestyle changes for type 2 diabetes remission

<img src="https://scx1.b-cdn.net/csz/news/800a/2022/bariatric-surgery-more.jpg" alt="La cirugía bariátrica es más eficaz que los cambios en el estilo de vida para la remisión de la diabetes tipo 2" title="diagrama CONSORT. Un total de 355 pacientes fueron previamente asignados aleatoriamente a los ensayos principales, 39 de los cuales no se sometieron a intervención y fueron excluidos del análisis. Se evaluó la elegibilidad y participación en el ensayo ARMMS-T2D de un total de 316 pacientes (N = 195 quirúrgicos y N = 121 médicos/estilo de vida). Se excluyó del análisis un total de 60 pacientes (N = 24 quirúrgicos y N = 36 médicos/de estilo de vida) debido a la falta de valores de HbA1c a los 3 años. Se incluyeron un total de 256 pacientes (N = 171 quirúrgicos y N = 85 médicos/estilo de vida) en el análisis de los resultados primarios y secundarios. Crédito: Diabetes Care (2022). DOI: 10.2337/dc21-2441″ width=”800″ height=”530″/>

CONSORT diagram. A total of 355 patients were previously randomized to the main trials, 39 of whom did not undergo intervention and were excluded from the analysis. A total of 316 patients (N = 195 surgical and N = 121 medical/lifestyle) were evaluated for eligibility and participation in the ARMMS-T2D trial. A total of 60 patients (N=24 surgical and N=36 medical/lifestyle) were excluded from the analysis due to missing HbA1c values ​​at 3 years. A total of 256 patients (N = 171 surgical and N = 85 medical/lifestyle) were included in the analysis of primary and secondary outcomes. Credit: diabetes care (2022). DOI: 10.2337/dc21-2441

Remission of type 2 diabetes is achieved more effectively and has longer lasting results with bariatric surgery than with medication and lifestyle changes.

A new study from the Pennington Biomedical Research Center, published in the journal diabetes care, evaluated 316 patients with type 2 diabetes to determine the effectiveness and long-term results of metabolic surgery. This is the largest study to date to evaluate metabolic surgery, also known as bariatric surgery, as a treatment for type 2 diabetes.

According to the Centers for Disease Control and Prevention, more than 34.2 million Americans, or 10.5 percent of the population, have type 2 diabetes. Obesity is a major contributing factor in the development of diabetes . About 90 percent of people with type 2 diabetes are overweight or obese. these intertwined they cause an enormous health burden both individually and societally.

“Treatment guidelines from the American Medical Association, the American Diabetes Association and many other leading medical organizations are that metabolic surgery is an effective treatment for type 2 diabetes,” said Pennington Biomedical CEO John Kirwan, Ph. .D., who directed the study. “Despite growing consensus, many health insurers do not provide coverage for metabolic surgery because we haven’t had a large enough randomized controlled trial looking at how long the results of surgery last relative to medications and .”

“Even when patients receive education on nutrition, exercise, self-management, and the newest diabetes medications on the market, only 2.6 percent of patients were able to achieve diabetes remission during the study,” notes Dr. Kirwan. “When we looked at patients who underwent metabolic surgery, even three years later, 37.5 percent had achieved a durable remission of their “, he added.

The study notes that fewer than 1 percent of people eligible for bariatric surgery receive the treatment, likely due to concerns by both patients and providers about long-term safety and lasting results.

The study also found that metabolic surgery was superior to medication and lifestyle changes in lowering HbA1c, fasting glucose, and other cardiovascular risk factors with substantially fewer medications.

“We hope that clinicians will be more confident in recommending to their patients, and that health insurers will see the health benefits and ultimately the savings that can be achieved by covering Dr. Kirwan said.


Greater Weight Loss After Bariatric Surgery Linked to Diabetes Remission


More information:
John P. Kirwan et al, Diabetes Remission in the Alliance of Randomized Trials of Medicine Versus Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D), diabetes care (2022). DOI: 10.2337/dc21-2441

Provided by the Pennington Biomedical Research Center

Citation: Bariatric Surgery More Effective Than Lifestyle Changes for Type 2 Diabetes Remission (September 1, 2022) Retrieved September 2, 2022 from https://medicalxpress.com/news/2022- 09-bariatric-surgery-effective-lifestyle-diabetes.html

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