Schizophrenia : Schizophrenia is a mental health problem. In which a person begins to consider his fantasies as reality. He is always confused. Schizophrenia is a mental problem that usually occurs during childhood or adolescence.
Researchers at Tokyo Medical and Dental University have conducted research on this topic. His team, led by Hiroki Shiwaku, found that some schizophrenic patients have an autoantibody. This is a type of protein usually produced by the immune system rather than viruses or bacteria. This means that autoantibodies cause schizophrenia-like behavior and brain changes.
What is research?
This research report published in Cell Reports Medicine describes a disorder that has many different causes and symptoms, making treatment very difficult. Schizophrenia is associated with genetic, environmental, and biological factors. New research has shown that autoantibodies can worsen the disorder in patients.
Brain-specific protein connection
The research team focused on a particular protein, called NCAM1. It helps brain cells communicate across synapses. Its special connections allow brain cells to join together in only one way. Previous studies had also suggested that NCAM1 might be involved in schizophrenia, so the researchers decided to investigate whether autoantibodies targeting this protein might be associated with the disorder.
How do autoantibodies affect the brain
The research team examined blood samples from 200 healthy patients and 200 schizophrenic patients. They found that only 12 patients had these specific autoantibodies, suggesting that these autoantibodies are not common. They may be important in a small subset of schizophrenia cases. The researchers studied how autoantibodies affect the brain. Autoantibodies were purified from some patients and injected into the brains of mice. As a result, the rats began to behave like people with schizophrenia, and changes also occurred in their brains. This revealed that in some schizophrenia patients, this may be related to the immune system mistakenly attacking the brain.
Treatment of schizophrenia
His treatment can last for a long time. If the patient’s problem is detected early and he is treated with psychological therapy and his family is also counseled, then the patient’s condition can be managed. strong>Disclaimer: Some information given in the news is based on media reports. Before implementing any suggestion, you must consult the concerned expert.
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