In research conducted so far, it was thought that the risk of cancer increased with age. Because immunity weakens with age. Furthermore, research has also revealed that over time, many genetic changes occur in cells and these genetic problems gradually begin to accumulate. This causes the development of cancer.
However, new research was conducted by researchers at Memorial Sloan Kettering Cancer Center (MSK) using a mouse model of lung cancer. In which it was revealed that the risk of cancer actually decreases with age. Dr Xueqian Zhuang explained in detail how lung cancer, like many other cancers, is usually treated around the age of 70. However, the chances of this happening decrease around age 80 or 85.
The risk of cancer decreases with age.
Our research helps show why this happens. With aging, cells lose the ability to make new cells and therefore the exponential growth of cancer decreases. The team tried to understand why cancer rates peak in early old age and then decline. They used a genetically modified mouse model of lung adenocarcinoma. It is a common lung cancer responsible for approximately 7% of cancer deaths worldwide.
Studying aging in models is challenging because it takes two years for mice to reach the equivalent of 65 to 70 years in humans. Although the process is time-consuming and resource-intensive, researchers have found it useful.
This was revealed in a research
This effect was also found to be reversible. Giving older mice more iron or reducing NUPR1 levels in their cells restored their regenerative capacity. We think this discovery could have immediate potential to help people. Currently, millions of people are living with inadequate lung function, especially after the COVID-19 pandemic, because their lungs have not fully recovered from an infection or for any other reason. Our experiments in mice have shown that iron intake can help regenerate the lungs, and we have very good ways of delivering drugs directly to the lungs, such as asthma inhalers. Restoring the regenerative capacity of lung cells can help prevent their ability to grow. can also increase. Therefore, Dr. Tamela said this product may not be suitable for people at high risk of cancer.
Disclaimer: Some information given in news is based on media reports. Before implementing any suggestion, you should consult the relevant expert.
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