What is Myasthenia Gravis?: Veteran actor Arun BaliKnown for his work in films 3 idiots, PK, Kedarnath, Panipat Etc., died on Saturday, October 7 after battling a rare disease called myasthenia gravis. Commonly known as MG, it is a neuromuscular disorder that causes weakness in the skeletal muscles, which are the muscles your body uses to move. This occurs when communication between nerve cells and muscles becomes impaired. This leads to impairment as it prevents critical muscle movement and thus, results in muscle weakness.Also Read – Kumkum actor Arun Bali dies at the age of 79 after suffering from a rare muscle disease in Mumbai
Myasthenia gravis causes and signs
Myasthenia gravis is caused by an autoimmune problem. Autoimmune disorders occur when the immune system mistakenly attacks healthy tissue. According to healthline.com, in this condition, antibodies, which are proteins that normally attack foreign, harmful substances in the body, attack the neuromuscular junction. When this happens the critical substance of communication between nerve cells and muscles is attacked. It damages the neuromuscular membrane because it reduces the effect of the neurotransmitter acetylcholine, a critical substance.
However, the exact cause of the autoimmune reaction is still uncertain for doctors. According to the Muscular Dystrophy Association, one theory is that certain viral or bacterial proteins can prompt the body to attack acetylcholine. According to the National Institutes of Health, MG occurs in people over the age of 40. Generally, women are diagnosed as younger individuals while men are diagnosed at age 60 or older.
Symptoms of Myasthenia Gravis:
According to Health Portal, “The main symptom of MG is weakness in the voluntary skeletal muscles, which are the muscles under your control. Failure of muscles to contract usually occurs because they cannot respond to nerve impulses. It results in weakness because there is no proper transmission of impulses which blocks the communication between nerves and muscles.
- Difficulty talking
- The problem is picking things up or walking upstairs
- Facial paralysis
- Difficulty breathing, swallowing or chewing
- tiredness
- raspy voice
- Eyelids pale
- double vision
The symptoms and degree of muscle weakness vary from day to day and from person to person. Severity of symptoms also depends on time.
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